What Are the Causes of an Unexplained Rash?

People with chronic fatigue syndrome sometimes develop an unexplained rash as well as muscle and joint pain.
Most rashes have some sort of explanation.
Some laundry detergents can cause skin reactions.
Allergies may manifest as skin rashes.
Hives can appear as an allergic reaction.
An allergic rash often causes redness and itching.
An unexplained rash is often caused by an allergic reaction to a foreign substance.
A topical cream can be applied to alleviate itchy skin.
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  • Written By: Alex Tree
  • Edited By: Melissa Wiley
  • Last Modified Date: 21 November 2014
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Some causes of an unexplained rash are an allergic reaction, abrasive clothing, and chronic fatigue syndrome. An allergic reaction is an especially common cause of unexplained rashes, but the patient often never finds out what he or she came into contact with that triggered the reaction. Chronic fatigue syndrome is a rarer cause, but researchers are unsure how rare due to how poorly understood the condition is and how many people go undiagnosed worldwide. In a few cases, the rash is caused by an immune response because of an autoimmune disorder.

Often an unexplained rash is caused by an allergic reaction to a foreign or unusual substance. Sometimes allergic reactions are minor and result only in symptoms such as rashes and itchiness, but other times can be more dangerous. One thing that often causes an unusual allergic reaction is a new laundry detergent, so it is usually a good idea to consider new substances that have been introduced into an environment when attempting to root out the cause of an allergic reaction. Bug bites, foods, and other substances can also result in an allergic reaction and unexplained rash.

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Sometimes an unexplained rash is caused by something as simple as abrasive clothing or friction. New clothing is more suspect than old clothing when people find themselves with an unexplained rash possibly due to abrasive material. Other times the rash is caused by friction, either friction against a person’s own skin, clothing, or something else that chafes the skin and eventually causes it to break out in a rash.

Chronic fatigue syndrome is a condition wherein the patient has unexplained fatigue for at least six months. There is no way of diagnosing a patient with chronic fatigue other than ruling out all other potential causes of the fatigue and considering any other symptoms. Some people with chronic fatigue syndrome develop an unexplained rash, while others suffer from headaches and low-grade afternoon fever. As causes of unexplained rashes go, this is believed to be a rather uncommon one, but the vast majority of people with chronic fatigue syndrome go undiagnosed.

Autoimmune progesterone dermatitis (APD) is a condition that causes women to develop rashes because of their menstrual cycle. This health problem is rare and not fully understood, but researchers believe the skin rash is a response to the hormonal changes in the woman’s body. Women with APD develop a rash before their period, which goes away within a few days of actually menstruating. Those who undergo hormone therapy, such as taking contraceptive pills, may be more likely to experience APD.

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serenesurface
Post 3

@ddljohn-- Autoimmune disorders and viral infections can cause rashes too. It's a good idea to see a doctor and get some tests done just in case.

I had an unexplained rash on my body last year and it turned out to be a hepatitis infection.

bear78
Post 2

@ddljohn-- Have you been eating a different food lately, or more of a particular food? Or did you change your hand soap or dish detergent?

I had this happen to me once and I started thinking about what I was doing different. I had been eating a lot of eggs, so I suspected that it might be a sensitivity or allergy to eggs. I stopped eating eggs but the rash didn't go away.

Then I decided to change my shower gel. I switched to pure olive oil soap in the bath and also to wash my hands. The difference was amazing. The rash disappeared in two days! I tried the shower gel again to see what happens and the rash returned when I used it!

If you have an unexplained rash and itching, you can try eliminating some things to see if it makes a difference. Even products we have been using for a long time can give us allergies.

ddljohn
Post 1

I developed an unexplained skin rash on my palms a few days ago. It's a red rash with white flakes. It developed suddenly and I honestly can't figure out what might have caused it.

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