Large intestine pain is very uncomfortable and can sometimes be something that is very simple or complex. If there is something in your family that is hereditary, this is sometimes the first thing that is considered.
My cousin was experiencing ongoing pain in the large intestine, and was diagnosed with Crohn's disease. His father also has the same thing, so it was one of the first things they began testing for. Many diseases are hereditary and this gives the doctors important information to know for your treatment.