It is alarming that congenital disorders are set in place even before a mother and father conceive their child. Studies show that a mother's and father's diet and glucose levels even before ovulation can effect the baby that is about to be conceived! It is also alarming that something as simple as a slanted/abnormal palpebral fissure can indicate that a newborn baby may have something more serious that just a cosmetic abnormality.
The palpebral fissure, although small, seems like it can effect the look and the condition of your eyes significantly. I always get debris to build up in my palpebral fissure after a long night of sleep. I have also had a sty on my palpebral fissure, and that was both painful and annoying. It took about a month for my sty to go completing away and for my palpebral fissure tissue around it to lose all it's skin irritation.