Mutsy - That is good to hear that your sister was able to find the right endocrinologist specialist.
I understand that not producing enough hormones can be a really frustrating situation because no matter how hard you try to lose weight, the weight does not come off.
Also, the lack of energy with this condition does not help. Restoring the hormonal balance makes you feel happy which is something that a person with his type of hormonal imbalance does not feel.
I also read that this type of problem tends to run in families.