What Is Etizolam?

The most common side effect of etizolam is sleepiness during daytime hours.
Etizolam may be used to treat depression.
Etizolam may be used to treat sleep disorders.
There is a significant increase in the likelihood of overdose when etizolam is combined with alcohol.
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  • Written By: L. Whitaker
  • Edited By: Heather Bailey
  • Last Modified Date: 06 December 2014
  • Copyright Protected:
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Etizolam is a thienodiazepine-based drug with multiple therapeutic properties that is sometimes used to treat anxiety, panic disorder, depression, or sleep disorders. At least one clinical trial has found etizolam to be more effective than a placebo in alleviating symptoms of depression and generalized anxiety disorder. This medication's effects are similar to those of the benzodiazepine drug family that includes lorazepam, clonazepam, and triazolam. As of 2011, etizolam was not approved for any use by the U.S. Food and Drug Administration, although it is used in some other countries. In Italy, etizolam is known by the trade name Depas, while in Japan it goes by a number of brand names such as Capsafe, Sedekopan, and Eticalm.

Side effects of etizolam are said to be mild or moderate, depending on the therapeutic dose given for specific conditions; the most common effect of etizolam is sleepiness during daytime hours. Dosage tends to be carefully monitored because of the risk of fatal overdose. This drug is typically reserved for short-term use, due to its chemical similarity to the benzodiazepines. The long-term effects of benzodiazepine medications can include disturbing nighttime dreams, memory loss, hostile behavior, and physical addiction. People who abruptly stop taking benzodiazepines tend to experience severe withdrawal symptoms, sometimes requiring hospitalization.

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Like its benzodiazepine-based cousins, etizolam is sometimes sought as an illicit drug for recreational use. Using this drug in search of a so-called high can be dangerous because of the impaired judgment it causes. In addition, there is a significant increase in the likelihood of overdose when etizolam is combined with alcohol.

Benzodiazepines can have varied therapeutic effects, depending on the dosage of the particular drug. These medications tend to be sedating at low doses, whereas higher doses can have anxiolytic or hynotic effects. In some medical cases, they can also be used to prevent seizures. Diazepam and alprazolam are two of the most common benzodiazepines to be obtained illegally for recreational use. Illicit users of cocaine or narcotic medications are said to be more likely to also abuse benzodiazepine drugs.

One benzodiazepine medicine that has gained media attention is flunitrazepam or Rohypnol®, also known informally as "roofies." In some high-profile cases, this medication has been used in combination with alcohol to render another person unconscious for the purpose of sexual assault. For this reason, flunitrazepam has become known as the so-called date rape drug.

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anon967132
Post 5

Etizolam is not authorized for use in America. You can get arrested for using it. If caught in your possession, it counts as a controlled substance.

SarahGen
Post 4

Etizolam is used in India. My doctor in India prescribed it for me when I was living there. I don't think this drug is more dangerous than any other anti-depressive drug out there. As long as it's taken under doctor supervision and in the recommended doses, it's fine.

Etizolam was actually very effective for me. It improved my mood immediately and it did not make me as drowsy as some other anti-depressive drugs I've tried. I also did not have a hard time coming off of it, but I did taper slowly. I think the FDA should reconsider.

literally45
Post 3

@ddljohn--Etizolam is not a benzodiazepine. It's a thienodiazepine. Thienodiazepine has thiophene and benzodiazepine doesn't. So they're not the same or even similar.

It might not be allowed in the US because of its potency. As far as I know, it's extremely potent, about ten times as strong as some benzodiazepines. So it's easy to overdose on it and yes, side effects will be greater than with benzodiazepines.

There is already a lot of benzo abuse in this country. So I'm glad that drugs like etizolam are kept out. This medication is not necessary for those who suffer from anxiety and depression. There are many other, effective and safer alternatives available.

ddljohn
Post 2

Why isn't etizolam approved in the US? Is it because more studies have to be done to prove its effectiveness? Or does it have too many side effects? But why would a developed country like Japan use it then? There are many benzodiazepine group of drugs on the market in the US, I don't know why etizolam is not allowed.

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