@pastanaga - I'm sure historically it hasn't been something to envy. I can almost guarantee that there have been people labeled as being demons or witches because they happened to be born with different colored eyes.
Or worse, the poor unfortunates who developed glaucoma or something back when people didn't know what that was. Then it would have really looked like they "made a deal with the devil".
Even today, I'm sure there are a lot of people who would find it hard to accept someone who looked that different (like people who have obvious birthmarks often have trouble). It's a sad state of affairs, frankly, because we should be past this kind of shallow bigotry.