Health
Fact-checked

At WiseGEEK, we're committed to delivering accurate, trustworthy information. Our expert-authored content is rigorously fact-checked and sourced from credible authorities. Discover how we uphold the highest standards in providing you with reliable knowledge.

Learn more...

What is Pheresis?

Tricia Christensen
Tricia Christensen
Tricia Christensen
Tricia Christensen

Pheresis is more commonly called apheresis, and it may be known by several other names. It is a procedure in medicine that involves drawing blood, separating it into certain elements and then replacing most of it back into the body. This could be medically indicated for a variety of reasons. Pheresis is sometimes used to collect some components of blood from a donor, and at other times it is employed to either temporarily or permanently remove some aspect of blood from an ill person as a treatment.

Blood has many components, and advances in science have found ways to break these components down when they are removed from the body. It is therefore possible to simply extract platelets from blood, or to take out blood plasma or the blood liquid. Alternately, white cells can be separated from blood. Whether the intent of pheresis is to donate a single aspect of blood or to remove it, procedure typically involves removing some whole blood and then returning part or most of it to the body.

Pheresis involves drawing blood.
Pheresis involves drawing blood.

The name may get more specific depending on type of blood product removed. Removal of plasma voluntarily or due to medical need is called plasmapheresis. Separation of leukocytes, which are a type of white blood cell, is referred to as leukopheresis, and platelet removal is typically named plateletpheresis.

There might be numerous reasons why removal and separation of blood products is considered as a treatment and the element of blood removed may vary based on what aspect of the blood is most involved in the disease. Some conditions that could call for pheresis of different forms included extremely high family inherited cholesterol, a variety of autoimmune diseases that result in abnormally high white blood cell counts, and conditions that result in very high platelet counts like thrombocytopenia.

Blood plasma, which is removed via plasmapheresis.
Blood plasma, which is removed via plasmapheresis.

Other times ill people benefit from donations of a single blood product. Platelets that are donated through pheresis by someone else may be used to help fight platelet loss caused by cancer treatment. Blood plasma is sometimes preferred to whole blood during some types of surgeries, and the list is fairly extensive.

There is need in many communities for pheresis donors. Apheresis procedures may take slightly longer than simple blood donation, and they may be done at different locations than blood donor centers, though this is not always the case. People who qualify to donate are usually subject to the same scrutiny as donors of any whole blood, and they will go through a screening to rule health conditions or medications that might disqualify them from donation. Many people do not ever know about this procedure until family members are ill. In these cases, healthy members of a family might be called upon to make donations to help an ailing relative or to understand the necessity of the procedure as a form of medical treatment.

Tricia Christensen
Tricia Christensen

Tricia has a Literature degree from Sonoma State University and has been a frequent WiseGEEK contributor for many years. She is especially passionate about reading and writing, although her other interests include medicine, art, film, history, politics, ethics, and religion. Tricia lives in Northern California and is currently working on her first novel.

Learn more...
Tricia Christensen
Tricia Christensen

Tricia has a Literature degree from Sonoma State University and has been a frequent WiseGEEK contributor for many years. She is especially passionate about reading and writing, although her other interests include medicine, art, film, history, politics, ethics, and religion. Tricia lives in Northern California and is currently working on her first novel.

Learn more...

Discussion Comments

anon87496

thrombocytopenia = Low platelet count

anon87467

"Apheresis procedures may take slightly longer than simple blood donation..."?

I am a regular platelet donor via apheresis at the Red Cross; I have also donated whole blood.

The latter, including pre-donation prep, takes about an hour; the former takes about two and half hours. Saying it takes 'slightly' longer than whole blood donations is an under exaggeration.

anon87425

Thrombocytopenia refers to a deficient number of platelets. Thrombocytosis refers to an increase in the number of platelets. It is incorrectly used in the third paragraph.

Post your comments
Login:
Forgot password?
Register:
    • Pheresis involves drawing blood.
      By: TRITOOTH
      Pheresis involves drawing blood.
    • Blood plasma, which is removed via plasmapheresis.
      By: dazzi-b
      Blood plasma, which is removed via plasmapheresis.
    • Pheresis can target specific types of white blood cells for removal.
      By: Alila Medical Media
      Pheresis can target specific types of white blood cells for removal.